1972 University of Minnesota B.S.        Field of Study: Biochemistry

1975 University of Minnesota M.S.       Field of Study: Biochemistry

1977 University of Minnesota Ph.D.      Field of Study: Biochemistry

1977-1985 |  Lecturer Prince of Songkla University
1985-1991 | Assistant professor Prince of Songkla University
1991-2008 | Associate professor Prince of Songkla University
2008 | Professor Prince of Songkla University
2015 | (retired) Professor Emerita and Director of CERB Prince of Songkla University

• Thai Academy of Science and Technology
• Science Society of Thailand
• Thai Society for Biotechnology

• 1969-1977 Thai Government Scholarship
• 1991 Taguchi Prize for Outstanding Young Researcher in Biotechnology, Thai Society for Biotechnology
• 1992 Outstanding Researcher, Prince of Songkla University
• 1994-1997 Thailand Research Fund (TRF) Research Scholar
• 1997 Member of the Thai Academy of Science and Technology
• 2000-2003 TRF Senior Research Scholar
• 2003-2006 TRF Senior Research Scholar
• 2012 Honors certificate from Senate of Thailand for successful commercialization of Hb-Extract product (derived from rubber latex serum)
• 2015 Professor Emerita, Prince of Songkla University

1. Yodthong, T., Kedjarune-Leggat, U., Smythe, C., Sukprasirt, P., Aroonkesorn, A., Wititsuwannakul, R., and Pitakpornpreecha, T. 2020. Enhancing Activity of Pleurotus sajor–caju (Fr.) Sing b-1, 3-Glucanoligosaccharide (Ps-GOS) on Proliferation, Differentiation, and Mineralization of MC3T3-E1 Cells through an Involvement of BMP-2/Runx2/MAPK/Wnt/b-Catenin Signaling Pathway. Biomolecules. 10, E190.
2. Yodthong, T., Kedjarune-Leggat, U., Smythe, C., Wititsuwannakul, R., and Pitakpornpreecha, T. 2018. L-Quebrachitol Promotes the Proliferation, Differentiation, and Mineralization of MC3T3-E1 Cells: Involvement of the BMP-2/Runx2/MAPK/Wnt/b-Catenin Signaling Pathway. Molecules. 23, E3086. 
3. Sukprasirt, P., Wititsuwannakul, R. 2014 A chitinolytic endochitinase and β- N-acetylglucosaminidase-based system from Hevea latex in generating N-acetylglucosamine from chitin. Phytochemistry 104,5-11.
4. Yuichi A., Takayama, D.,Ogata, Y., Sakura, N., Asawatreratanakul, K., Wititsuwannakul,D., Wititsuwannakul, R., Shibata, D., Koyama, T, Nakayama, T. 2014 Identification of laticifer-specific genes and their promoter regions from a natural rubber producing plant Hevea brasiliensis. Plant Science 225,1-8
5. Jantaramanant, P., Sermwittayawong, D., Noipha, K., Nongporn Hutadilok-Towatana, N., Wititsuwannakul, R. 2014 β -glucan-containing polysaccharide extract from the grey oyster mushroom [Pleurotus sajor-caju (Fr.) Sing.] stimulates glucose uptake by the L6 myotubes. International Food Research Journal 21,779-
6. Pitakpornpreecha,T., Plubrukarn, A., Wititsuwannakul, R. 2012 Quantification of 5′-deoxy-5′-methylthioadenosine in heat-treated natural rubber latex serum. Phytochemical Analysis 23(1)12-15.
7. Chotigeat,W. Duangchu S., Wititsuwannakun, R, Phongdara A. 2009. Cloning and characterization of pectate lyase from Hevea brasiliensis. Plant physiology and biochemistry 47, 243-247.
8. Tosaka, M.,Furutani, M.,Tsuji, M.,Ikeda, Y., Kohjiya, S.,Wititsuwannakul, D., Wititsuwannakul, R., Nagayama, K., Danev, R. 2009. Strain-induced crystallization of fractionated natural rubber from fresh latex. J. Soc. Mater. Sci. 58, 5-10.
9. Wititsuwannakul, R.., Pasitikul, P., Kanomwiroon, K., Wititsuwannakul, D. 2008. A role for a Hevea latex lectin-like protein in mediating rubber particle aggregation and latex coagulation. Phytochemistry 69, 339-347.
10. Wititsuwannakul, R., Pasitkul, P., Jewtragoon , P., Wititsuwannakul D., 2008. Hevea latex lectin binding protein in C-serum as an anti-latex coagulating factor and its role in a proposed new model for latex coagulation. Phytochemistry, 69, 656-662.
11. Wititsuwannakul, R., Rukseree, K., Kanokwiroon , Wititsuwannakul D. 2008. A rubber particle protein specific for Hevea latex lectin binding involved in latex coagulation. Phytochemistry 69, 1111-1118.
12. Phatthiya, A., Takahashi, S., Chareonthiphakorn, N., Koyama, T., Wititsuwannakul, D., Wititsuwannakul, R. 2008 Cloning and expression of the gene encoding solanesyl diphosphate synthase from Hevea brasiliensis. Plant Sci. 172, 824-831.
13. Yoonram, K., Takahashi, S., Rattanapittayaporn, A., Koyama, T., Wititsuwannakul, D., Wititsuwannakul, R. 2008 cDNA, from Hevea brasiliensis, encoding 1-deoxy-D-xylulose-5-phosphate reductoisomerase. Plant Sci. 175, 694-700.
14. Kanokwiroon, K., Teanpaisan, R., Wititsuwannakul, D., Hooper, A.B., Wititsuwannakul, R. 2008. Antimicrobial activity of a protein purified from the latex of Hevea brasiliensis on oral microorganisms. Mycose 51, 301-307.
15. Mengumpun, K., Tayapiwatana, C., Hamilton, R.G., Sangsupawanich, P., Wititsuwannakul, R. 2008. Hydrophobic allergens from the bottom fraction membrane of Hevea brasiliensis. Asian Pacific Journal of Allergy and Immunology 26, 129-136.
16. Sritanyarat, W., Pearce, G., Siems, W.F., Ryan, C.A., Wititsuwannakul, R., Wititsuwannakul, D. 2006. Isolation and characterization of isoinhibitors of the potato protease inhibitor I family from the latex of the rubber trees, Hevea brasiliensis. Phytochemistry, 67, 1644-1650.
17. Wititsuwaannakul, D., Rattanapittayaporn A., Koyama, T. and Wititsuwaannakul, R. 2004. Involvement of Hevea latex organnelle membrane proteins in rubber biosynthesis activity and regulatory function. Macromol. Biosci. 4, 314-323.
18. Rattanapittayaporn, A., Wititsuwannakul, D. and Wititsuwannakul, R. 2004 Significant role of bacterial undecaprenyl diphosphate (C55-UPP) for rubber biosymthesis by Hevea latex enzymes. Macromol. Biosci. 4, 1039-1052.
19. Wititsuwannakul, D., Rattanapittayaporn, A. and Wititsuwannakul, R., 2003. Rubber biosynthesis by the Hevea latex bottom fraction membrane. J. Appl. Polym Sci. 86, 90-96.
20. Takaya,A., Zhang Y-W, Asawatretanakul, K., and Wititsuwannakul, D., Wititsuwannakul, R., Takahashi, S. and Koyama, T. 2003 Cloning, expression and characterization of a functional cDNA clone encoding geranyl diphosphate synthesas of Hevea brasiliensis. Biochem. Biophys. Acta 1625, 214-220.

21. Asawatreratanakul, K., Zhang,Y-W., Wititsuwannakul,D., Wititsuwannakul, R., Takahashi, S. and Koyama, T. 2003. Molecular Cloning, expression and characterization of cDNA encoding rubber transferase from Hevea brasiliensis – A key factor participating in natural rubber biosynthesis. Eur. J. Biochem. 270, 4671-4680.

22. Wititsuwannakul, D., Chareonthiphakorn, N., Pace, M., Wititsuwannakul, R. 2002. Polyphenol oxidases from latex of Hevea brasiliensis: purification and characterization. Phytochemistry, 61, 115-121.

23. Chareonthiphakorn, N., Wititsuwannakul, D., Golan-Goldhirsh , A., Wititsuwannakul, R. 2002. Purification and characterization of NAD(P)H quinone reductase from the latex of Hevea brasiliensis Müll.- Arg. (Euphorbiaceae). Phytochemistry, 61, 123-128.

24. Ohya, N., Tanaka, Y., Wititsuwannakul, R., Koyama, T. 2000. Activity of rubber transferase and rubber particles size in Hevea latex. J. Rubb. Research, 3, 214-221.

25. Tateyama, S., Wititsuwannakul, R., Wititsuwannakul, D., Sagami, H., Ogura, K.1999. Dolichols of rubber plant, ginkgo and pine. Phytochemistry, 51, 11-15.

26. Wititsuwannakul, R., Wititsuwannakul, D. and Sakulborirug. C. 1998 A lectin from the bark of the rubber tree (Hevea brasiliensis). Phytochemistry 47,183-187.

27. Wititsuwannakul, R., Wititsuwannakul, D., Sattaysevana, B., Pasitkul, P. 1997. Peroxidase from Hevea brasiliensis bark: purification and properties. Phytochemistry, 44, 237-241.

28. Teeraratkul, A., Dangsuwan, T., Wititsuwannakul, R., Kerdsomnuk, S., Sawaengsakdi, L., Roengrak, S., Wititsuwannakul, D., Vichayanon, P. 1997. Epidemiology of latex allergy among healthcare personnel at Siriraj Hospital. Siriraj Hosp Gaz 46, 837-845.

29. Tangpakdee, J., Tanaka, Y., Ogura, K., Koyama, T., Wititsuwannakul, R., Wititsuwannakul, D., Asawatreratanakul, K.1997. Isopentenyl diphosphate isomerase and prenyl transferase activities in bottom fraction and c-serum from Hevea latex. Phytochemistry, 45, 261-267.

30. Tangpakdee, J., Tanaka, Y., Ogura, K., Koyama, T., Wititsuwannakul, R., Wititsuwannakul, D. 1997. Rubber formation by fresh bottom fraction of Hevea latex. Phytochemistry, 45, 269-274.

31. Tangpakdee, J., Tanaka, Y., Ogura, K., Koyama,T., Wititsuwannakul, R., Chareonthiphakorn, N.1997. Structure of in vitro synthesized rubber from fresh bottom fraction of Hevea latex. Phytochemistry, 45, 275-281.

32. Koyama,T., Wititsuwannakul, D., Asawatreratanakul, K., Wititsuwannakul, R., Ohya, N., Tanaka, Y., Ogura, K. 1996. Isopentenyl diphosphate isomerase in rubber latex. Phytochemistry, 43, 769-772.

33. Tangpakdee, J.,Tanaka, Y., Wititsuwannakul, R. ,Chareonthiphakorn, N. 1996. Possible mechanisms controlling molecular weight of rubbers in Hevea brasiliensis. Phytochemistry, 42, 353-355.

34. Tanaka,Y., Eng, A.H., Ohya, N., Nishiyama, N., Tangpakdee, J., Kawahara, S., Wititsuwannakul, R. 1996. Initiation of rubber biosynthesis in Hevea brasiliensis: characterization of initiating species by structural analysis. Phytochemistry, 41,1501-1505.

35. Suvachittanont, W., Wititsuwannakul, R. 1995. 3-Hydroxy-3-methylglutaryl-coenzyme, a synthase in Hevea brasiliensis.1995. Phytochemistry, 40, 757-761.

36. Churngchow, N., Suntaro, A. and Wititsuwannakul, R. 1995. β-1,3-Glucanase isozymes from latex of Hevea brasiliensis. Phytochemistry. 39, 505-509.

37. Koyama, T., Asawatreratanakul, K., Wititsuwannakul, D., Wititsuwannakul, R., Ogura, K.1995 Analysis of prenyl transferase reaction products from C-serum of Hevea brasiliensis. In: Svasti J. et al. editors. Biopolymers and Bioproducts:Structure, Function and Applications [IUBMB Symposium no. 239] pp.608-612.

38. Asawatreratanakul, K., Koyama, T., Wititsuwannakul, D., Wititsuwannakul, R., Ogura, K.1995. Characterization of Hevea isopentenyl diphosphate isomerase. In: Svasti J. et al. editors. Biopolymers and Bioproducts:Structure, Function and Applications [IUBMB Symposium no. 239] pp.613-618.

39. Wititsuwannakul, R., Wititsuwannakul, D., Suwanmanee, P. 1990. 3-Hydroxy-3-methylglutaryl coenzyme A reductase from the latex of Hevea brasiliensis. Phytochemistry 29, 1401-1403.

40. Wititsuwannakul, R., Wititsuwannakul, D., Dumkong, P. 1990. Hevea calmodulin: Regulation of the activity of latex 3-hydroxy-3-methylglutaryl coenzyme a reductase. Phytochemistry 29, 1755-1758.

41. Wititsuwannakul, R. 1985. Diurnal variation of 3-hydroxy 3-methylglutaryl coenzyme A reductase activity in latex of Hevea brasiliensis and its relation to rubber content. Experientia 42, 44-45.

• Wititsuwannakul,D. and Witisuwannakul, R. 2005 Biochemistry of Natural Rubber
  and Structure of Latex. in: “ Biopolymers for Medical and Pharmaceutical Applications” pp.35-85 (Eds: Alexander Steinbuchel and Robert H. Marchessault) WILEY-VCH. Weiheim, Germany.
• Wititsuwannakul,D. and Witisuwannakul, R. 2005 Biochemistry of Natural Rubber
  and Structure of Latex. in: “Biotechnology of Biopolymers From Synthesis to Patents”
  pp.75-90 (Eds: Alexander Steinbuchel and and Y. Doi ) ,WILEY-VCH. Weiheim,
  Germany.
• Wititsuwannakul,D. and Witisuwannakul, R. 2001. Biochemistry of Natural Rubber
  and Structure of Latex. in: “ Biopolymers” pp.151-201. (Eds: Alexander Steinbuchel and Tanetoshi Koyama) ,WILEY-VCH. Weiheim, Germany.

• Wititsuwannakul, R.(Inventor) “Skin whitening biochemicals extracted from natural rubber latex serum” Thai Petty Patent No. 4907(2009).
• Wititsuwannakul, R. (Inventor) “Skin whitening composition containing extracts derived from natural rubber latex” Singapore Patent No. 144020 (2010).
• Wititsuwannakul, R.(Inventor) “Skin whitening composition containing extracts derived from natural rubber latex” The People’s Replubilc of China Patent No. ZL10166303.0 (2013)
• Wititsuwannakul, R.(Inventor) “Skin whitening composition containing extracts derived from natural rubber latex” Malaysia Patent No. MY153171 (2015)